精品国产一区二区桃色

ASBMB Annual Meeting

Biochemists bite back

Undergraduates catalog Texas mosquitos that carry known and novel viruses
Marissa Locke Rottinghaus
March 25, 2024

During the hot summer months in Houston, citronella candles, bug sprays, zappers and fly swatters sell like hotcakes so people can keep mosquitos at bay. However, students at a local university invite the pests into their backyards. Using large barrel traps, they have collected hundreds of mosquitos to investigate what viruses the insects are spreading in the Bayou City and across the Lone Star State.

Mosquitos, ticks and fleas, also known as vectors, carry myriad viruses, bacteria and parasites. These pests pathogens to animals and humans via their saliva during a bite. But don’t worry too much: The chance of developing a viral disease, such as West Nile virus, after a mosquito bite is just in the U.S.

Ava Ngo
Left: Undergraduate researcher William Maldonado performs DNA and RNA extractions on mosquito samples in the lab at the University of St. Thomas in Houston. Right: University of St. Thomas undergraduate researcher Angelika Jordan sets up a mosquito trap in her backyard in Houston.

However, the mosquito population in North America has increased the past 50 years due to climate change. Now, health officials are seeing some that previously were found in only tropical regions a decade ago pop up across the southern U.S.

“Even though the field of microbiology has been around for centuries, it's only now that we're beginning to uncover much of its diversity,” , professor and chair of biology at the University of St. Thomas and project supervisor, said.

Therefore, researchers at UST began to do their part in tracking mosquito species and the viruses they carry across Houston.

“Knowing where viruses exist and how they might move to new environments or new hosts is important for better surveillance, tracking and prevention of known diseases, as well as emergent and novel diseases that might challenge humans in the future,” , an undergraduate researcher at UST, said.

Ngo worked with fellow undergraduates Angelika Jordan and William Maldonado to capture mosquitos across town. Their are designed to simulate a human being by imitating the visual signals and convection currents of a body.

After capturing the mosquitos and extracting their RNA and DNA, the team worked with the UST computer science department to perform metagenomics on the samples. The hundreds of mosquitos they gathered collectively carried dozens of viruses, such as West Nile virus, Dengue virus and others.

According to , a professor of biology at UST and project supervisor, the most surprising virus they uncovered was Lauvirus, which is native to Southeast Asia.

“Lauvirus interests me the most, because Houston is right on the shipping channel,” Rosell said.

Left to right, undergraduate researcher Ava Ngo, project supervisor and department chair Maia Larios and project supervisor and professor Rosemarie Rosell.

The Houston Ship Channel stretches 52 miles, starting at the Gulf of Mexico and ending just four miles east of downtown.

“We have all these ginormous shipping containers come in on ships from all over the world,” Rosell said. “These containers have water inside them, which can carry mosquitos with different types of viruses and viral loads.”

The team also found that different mosquito species localized to specific parts of the Houston metro area. In the wooded north, Aedes aegypti mosquitos dominate, and Culex quinquefasciatus mosquitos primarily inhabit the south.

In addition to finding viruses with known genomes, the team identified thousands of uncharacterized viral sequences, which they plan to investigate in future studies.

“We are filling in gaps in our understanding of diversity in nature, which ties into health and conservation and affects the human existence,” Larios said. “It’s not just about the ‘sexy’ diseases, but it is also about understanding what kinds of viruses exist in the environment and how they move.”
 

Details

Ava Ngo will present this research from 5:30 to 6:30 p.m. CDT on Monday, March 25, at  2024, the 精品国产一区二区桃色 annual meeting in San Antonio. Her poster is at Board 301.

Abstract title: Characterizing Houston’s viral strains carried by mosquitos via metagenomics

Enjoy reading ASBMB Today?

Become a member to receive the print edition four times a year and the digital edition monthly.

Learn more
Marissa Locke Rottinghaus

Marissa Locke Rottinghaus is the Editorial Content Manager for ASBMB.

Get the latest from ASBMB Today

Enter your email address, and we鈥檒l send you a weekly email with recent articles, interviews and more.

Latest in Science

Science highlights or most popular articles

Understanding the roles of extracellular matrix and vesicles in valvular disease
Profile

Understanding the roles of extracellular matrix and vesicles in valvular disease

Oct. 30, 2025

MOSAIC scholar Cassandra Clift uses mass spectrometry and multiomics to study cardiovascular calcification and collagen dysregulation, bridging her background in bioengineering and biology to investigate extracellular vesicles and heart disease.

Lipid profiles reveal sex differences in type 2 diabetes
Journal News

Lipid profiles reveal sex differences in type 2 diabetes

Oct. 29, 2025

Researchers explored the lipid profiles of individuals with type 2 diabetes and identified potentially useful lipid biomarkers for this condition.

Serum lipids may predict early diabetes risk
Journal News

Serum lipids may predict early diabetes risk

Oct. 29, 2025

Researchers found that levels of two key fatty acids may predict worsening tolerance for glucose, independent of body fat and insulin levels. In turn, these fatty acids may serve as early T2D biomarkers.

Sex and diet shape fat tissue lipid profiles in obesity
Journal News

Sex and diet shape fat tissue lipid profiles in obesity

Oct. 29, 2025

Researchers found that sex hormone levels and diet both influence inflammation and lipid composition in obesity.

Mapping the placenta鈥檚 hormone network
Journal News

Mapping the placenta鈥檚 hormone network

Oct. 21, 2025

Study uncovers how the placenta actively metabolizes not only glucocorticoids but also novel androgens and progesterones, reshaping our understanding of pregnancy and its complications.

Biochemists and molecular biologists sweep major 2025 honors
News

Biochemists and molecular biologists sweep major 2025 honors

Oct. 20, 2025

Recent Nobel, MacArthur and Kimberly Prize honorees highlight the power of biochemistry and molecular biology to drive discovery, including immune tolerance, vaccine design and metabolic disease, and to advance medicine and improve human health.