Second annual JBC Methods Madness tournament begins next week
Calling all scientists! The Journal of Biological Chemistry’s second annual Methods Madness tournament is here.
Last year’s tournament came down to the wire with #TeamCryo scraping by #TeamMassSpec to be crowned the first ever champion. Can #TeamCryo repeat this year? Will #TeamMassSpec get revenge? Will both be upset by a new contender? Now is your chance to decide who makes it through.
The madness begins on Monday. (See tournament schedule below). Submit your bracket by Sunday for a chance to win a $100 gift card.
Round 1: The Scientific 16
Vote for your favorite methods by participating in polls posted by .
Monday, March 15
9 a.m. – #TeamMassSpec vs. #TeamFRET
2 p.m. – #TeamImmuno vs. #TeamXRC
Tuesday, March 16
9 a.m. – #TeamCryo vs. #TeamMachine
2 p.m. – #TeamiPSC vs. #TeamLiveCell
Wednesday, March 17
9 a.m. – #TeamPCR vs. #TeamChroma
2 p.m. – #TeamCloning vs. #TeamNMR
Thursday, March 18
9 a.m. – #TeamCRISPR vs. #TeamSuperRes
2 p.m. – #TeamOmics vs. #TeamOpto
All times Eastern.
A note about JBC methods
It's well known that science progresses by building on the shoulders of those who came before. That's especially true for papers that report new tools — genetic constructs, small molecules, model organisms, etc. — that can be directly used by colleagues to jump-start a new project or resolve a technical hurdle. And at JBC, our high standards for rigor and reproducibility mean that readers can trust published tools to work as promised.
— Lila Gierasch, JBC editor-in-chief
Enjoy reading ASBMB Today?
Become a member to receive the print edition four times a year and the digital edition monthly.
Learn moreGet the latest from ASBMB Today
Enter your email address, and we鈥檒l send you a weekly email with recent articles, interviews and more.
Latest in Science
Science highlights or most popular articles

Understanding the roles of extracellular matrix and vesicles in valvular disease
MOSAIC scholar Cassandra Clift uses mass spectrometry and multiomics to study cardiovascular calcification and collagen dysregulation, bridging her background in bioengineering and biology to investigate extracellular vesicles and heart disease.

Lipid profiles reveal sex differences in type 2 diabetes
Researchers explored the lipid profiles of individuals with type 2 diabetes and identified potentially useful lipid biomarkers for this condition.

Serum lipids may predict early diabetes risk
Researchers found that levels of two key fatty acids may predict worsening tolerance for glucose, independent of body fat and insulin levels. In turn, these fatty acids may serve as early T2D biomarkers.

Sex and diet shape fat tissue lipid profiles in obesity
Researchers found that sex hormone levels and diet both influence inflammation and lipid composition in obesity.

Mapping the placenta鈥檚 hormone network
Study uncovers how the placenta actively metabolizes not only glucocorticoids but also novel androgens and progesterones, reshaping our understanding of pregnancy and its complications.

Biochemists and molecular biologists sweep major 2025 honors
Recent Nobel, MacArthur and Kimberly Prize honorees highlight the power of biochemistry and molecular biology to drive discovery, including immune tolerance, vaccine design and metabolic disease, and to advance medicine and improve human health.